Thursday, June 6, 2019

Publications and Talks



Peer-Reviewed Publications

1. Brandt CR, Kintner RL, Pumfery AM, Visalli RJ, and Grau DR. The herpes simplex virus ribonucleotide reductase is required for ocular virulence. J Gen Virol 72:2043-2049, 1991.
2. Balish MJ, Abrams ME, Pumfery AM, and Brandt CR. Enhanced inhibition of herpes simplex virus type 1 growth in human corneal fibroblasts by combinations of interferon α and γ. J Inf Dis 166:1401-1403, 1992.
3. Brandt CR, Pumfery AM, Micales B, Bindley CD, Lyons GE, Sramek SJ, and Wallow IHL. Renin mRNA is synthesized locally in rat ocular tissues. Curr Eye Res 13:755-763, 1994.
4. Pumfery AM and Brandt CR.  Thymidine kinase and susceptibility to interferon are not involved in the increased virulence of recombinant viruses isolated following mixed ocular infection with HSV-1 strains OD4 and CJ394.  Ophthalmic Res 28:125-129, 1996.
5. Muralidhar S, Pumfery AM, Hassani M, Sadaie MR, Azumi N, Kishishita M, Brady JN, Doniger J, Medveczky P, and Rosenthal LJ.  Identification of kaposin (open reading fram K12) as a human herpes virus 8 (kaposi’s sarcoma-associated herpes virus) transforming gene.  J Virol 72:4980, 1998.
6. de la Fuente C, Santiago F, Deng L, Eadie C, Zilberman I, Kehn K, Maddukuri A, Baylor S, Wu K, Lee CG, Pumfery A, and Kashanchi F.  Gene expression profile of HIV-1 tat expressing cells: a close interplay between proliferative and differentiation signals.  BMC Biochem 3:14, 2002.
7. Deng L, Ammosova T, Pumfery A, Kashanchi F, and Nekhai S. HIV-1 Tat interaction with RNA polymerase II CTD and a dynamic association with CDK2 induces CTD phosphorylation and transcription from HIV-1 promoter. J Biol Chem 277:33922-33929, 2002. 
8. de la Fuente C, Wang L, Wang D, Deng L,  Wu K, Hong L, Stein D, Denny T, Coffman F, Kehn K, Baylor S, Maddurkuri A, Pumfery AM, and Kashanchi F.  Paradoxical effects of a stress signal on pro-and anti-apoptotic machinery. Mol Cell Biochem 245:99-113, 2003.
9. Brandt CR, Kolb AW, Shah DD, Pumfery AM, Kintner RL, Jaehnig E, Van Gompel JJ. Multiple determinants contribute to the virulence of HSV ocular and CNS infection and identification of serine 34 of the US1 gene as an ocular disease determinant. Invest Ophthalmol Vis Sci 44:2657-2668, 2003.
10. de la Fuente C, Maddukuri A, Kehn K, Baylor SY, Deng L, Pumfery A, and Kashanchi F. Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics. Curr HIV Res 1:131-152, 2003.
11. Pumfery A, Deng L, Maddukuri A, de la Fuente C, Li H, Wade JD, Lambert P, Kumar A, and Kashanchi F. Chromatin remodeling and modification during HIV-1 Tat-activated transcription. Curr HIV Res 1:261-274, 2003.
12. Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A. Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb  kinase during human immunodeficiency virus type 1 transcription. J Virol 78:13522-13533, 2004.
13. Ghedin E, Pumfery A, de la Fuente C, Yao K, Miller N, Lacoste V, Fraser C, Quackenbush J, Jacobson S, and Kashanchi F. Use of a multi‑virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP‑chip analysis. Retrovirol 1:10, 2004.
14. Lacoste V, de la Fuente C, Kashanchi F, and Pumfery A. Kaposi’s sarcoma-associated herpesvirus immediate early gene activity. Front Biosci 9:2245-2272, 2004. 
15. Kehn K, Berro R, de la Fuente C, Strouss K, Ghedin E, Dadgar S, Bottazzi ME, Pumfery A, and Kashanchi F. Mechanisms of HTLV-1 transformation. Front Biosci 9:2347-2372, 2004.
16. Seelamgari A, Maddukuri A, Berro R, de la Fuente C, Kehn K, Deng L, Dadgar S, Bottazzi ME, Ghedin E, Pumfery A, and Kashanchi F. Role of viral regulatory and accessory proteins in HIV-1 replication. Front Biosci 9:2388-2413, 2004.
17. Kehn K, Deng L, de la Fuente C, Strouss K, Wu K, Maddukuri A, Baylor S, Rufner R, Pumfery A, Bottazzi ME, and Kashanchi F. The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells. Retrovirol 1:6, 2004.
18. Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, and Kashanchi F. Protein profile of Tax-associated complexes. J Biol Chem 279:495-508, 2004.
19. Agbottah E, de La Fuente C, Nekhai S, Barnett A,  Gianella-Borradori A, Pumfery A, Kashanchi F. Antiviral activity of Cyc202 in HIV-1 infected cells. J Biol Chem 280:3029-4204, 2005.
20. Kehn K, de la Fuente C, Strouss K, Berro R, Jiang H, Brady J, Mahieux R, Pumfery A, Bottazzi ME,  Kashanchi F. The HTLV-I Tax oncoprotein targets the Retinoblastoma (Rb) protein for proteasomal degradation. Oncogene 24:525-540, 2005.
21. Liang WS, Maddukuri A, Teslovich T, de la Fuente C, Seelamgari A, Kehn K, Baylor S, Hautaniemi S, Pumfery A, Stephan DA, and Kashanchi F. Therapeutic Targets For HIV-1 Infection In The Host Proteome. Retrovirology 2:20, 2005.
22. Pumfery A, de la Fuente C, Berro R, Nekhai S, Kashanchi F, and Chao SH. Potential use of pharmacological cyclin‑dependent kinase inhibitors as anti‑HIV therapeutics. Curr Pharm Design, 12:1949-1961. 2006.
23. Agbottah E, Zhang N, Dadgar S, Pumfery A, Wade JD, Zeng C, and Kashanchi F. Inhibition of HIV-1 virus replication using small soluble Tat peptides. Virology 345:373. 2006.
24. Berro R, Kehn K, de la Fuente C, Pumfery A, Adair R, Wade J, Colberg-Poely A, Hiscott J, and Kashanchi F. Acetylated Tat regulates HIV-1 splicing through its interaction with the splicing regulator, p32. J Virol 80:3189. 2006.
25. de la Fuente C, Gupta MV, Klase Z, Strouss K, CahanP, McCaffery T, Galante A, Soteropoulous P, Pumfery A, Fujii M, and Kashanchi F. Involvement of HTLV-1 Tax and CREB in aneuploidy: A bioinformatics approach. Retrovirology. 3:43, 2006.
26. Pumfery A, de la Fuente C, and Kashanchi F. HTLV-1 Tax: Centrosome amplification and cancer. Retrovirology, 3:50, 2006.
27. Agbottah E, Deng L, Pumfery A, and Kashanchi F. Effect of a chromatin remodeling complex on HIV-1 activated transcription. Retrovirology. 3:48, 2006.
28. Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Agbottah E, Vertes A, Nekhai S, and Kashanchi F. Identifying the membrane proteome of HIV-1 infected cells. J Biol Chem. 282:8207-18, 2007.
`29. Mody M, Dharker N, Bloomston M, Glickman T, McCaffrey T, Yang Z, Pumfery A, Lee D, Ringel MD, and Pinzone JJ. Rosiglitazone Sensitises MDA-MB-231 Breast Cancer Cells to Anti-tumour Effects of TNF, CH11 and CYC202. Endocr Relat Cancer. 4(2):305-15, 2007

Book Chapters
1. Brandt CR, Kintner RL, Visalli RJ, and Pumfery AM. Ribonucleotide reductase and the ocular virulence of HSV-1, pp136-150. in Pathogenicity of human herpes viruses and specific pathogenicity genes, Frontiers in Virology vol. 3. G Daria and Y Becher, eds. 1994, Springer-Verlag, Berlin.
2. Pumfery A, Berro R, and Kashanchi F. Proteomics of Viruses. In Medical Applications of Mass Spectrometry. K Vekey, A Telekes, A Vertes, Eds. 2008. Elsevier Publishers

Invited Presentations

1. Pumfery A.  “DNA Fingerprinting Workshop”. Essex County Essex County College Division of Biology and Chemistry, Newark NJ. November 16, 2017
2. Pumfery A. “DNA Fingerprinting and the Law”, panel discussion. Essex County Essex County College Division of Biology and Chemistry, Newark NJ. April 2, 2015.
3. Pumfery A. “The Virology of Ebola”. Essex County College Division of Biology and Chemistry, Newark NJ. December 11, 2014.
4. Pumfery A. “Ebola Virus Panel Discussion”. Essex County College, Newark NJ. November 13, 2014.
5. Pumfery A. “Influenza, Colds, and Vaccines”. Essex County College Division of Biology and Chemistry, Newark NJ. February 28, 2013.
6. Pumfery A. “The Human Herpesviruses”. Essex County College Division of Biology and Chemistry, Newark NJ. November 3, 2011.
7. Pumfery A. “Issues of Gender Equity” 90th National meeting /Graduate Women in Science. Cornell University, Ithaca NY. June 18, 2011.
8. Pumfery A. “The HPV Vaccine and Prevention of Cervical Cancer”. Graduate Women in Science Kappa chapter. March 19, 2007.
9. Pumfery AM. “Kinases as Antivirals”. Seton Hall University Department of Chemistry and Biochemistry. April 4, 2006.
Conferences
1. The 12th Annual Workshop on Kaposi's Sarcoma-Associated Herpesvirus (KSHV) and Related Agents, Charleston, South Carolina (September 13-16, 2009). “Characterization of KSHV ORF11 as a possible inhibitor of ORF50/Rta” C. N. Ramirez, S.A. Creighton, J. Guito, D.M. Lukac, and A. M. Pumfery           
2. 33rd Annual International Herpesvirus Workshop, Estoril, Portugal (July 27 - August 1, 2008).  Characterization of Kaposi’s sarcoma-associated herpesvirus ORF11” A.M. Pumfery and C.N. Ramirez
3. 10th International Conference on Malignancies in AIDS, Bethesda MD (October 16-17, 2006). “Involvement of Cyclin Dependent Kinases in KSHV Gene Expression”. V. Lacoste, C. de la Fuente, R. Berro, S. Jacobson, E. Ghedin, F. Kashanchi, A. Pumfery
4. 25th International Herpesvirus Workshop. Boston, MA (1999). “The human herpesvirus 6 Ts protein inhibits HIV-1 replication and the minimal domain for suppression of the HIV-1 LTR lies between amino acids 147 and 225”. A.M. Pumfery, F.Kashanchi, and L.J.Rosenthal
5. International Conference on Herpetic Eye Diseases. New Orleans, LA. (1992). “Biological and histological characterization of HSV-1 recombinants with increased ocular and neurovirulence”. Pumfery AM, Brandt CR, and Dubielzig RR.